Search on: VERY-LOW-DENSITY LIPOPROTEINS 
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Descriptor English:   Lipoproteins, VLDL 
Descriptor Spanish:   Lipoproteínas VLDL 
Descriptor Portuguese:   Lipoproteínas VLDL 
Synonyms English:   Prebeta-Lipoproteins
Very-Low-Density Lipoproteins  
Tree Number:   D10.532.599
D12.776.521.622
Definition English:   A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues. 
Indexing Annotation English:   hypoprebetalipoproteinemia = LIPOPROTEINS, VLDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); /defic: consider also HYPOLIPOPROTEINEMIAS
History Note English:   74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   8253 
Unique Identifier:   D008079 

Occurrence in VHL: 		 

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